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BME Seminars: Nicolas Schweighofer


This friday 22th march, the BME seminars will host a lecture of Nicolas Schweighofer entitled "Models and neural bases of motor adaptation with applications to neuro-rehabilitation post-stroke". Nicolas Schweighofer is an Associate Professor in the Division of Biokinesiology and Physical Therapy at the University of Southern California, Los Angeles (USA). (See attached flyer)

Abstract:
"Although our understanding of the mechanisms underlying motor adaptation has greatly benefited from previous computational models, the architecture of motor memory is still uncertain. Here, we systematically testing possible architectures via a combination of computer simulations and of a dual visuo-motor adaptation experiment. Our result suggests that during motor adaptation fast and slow processes are updated simultaneously from the same motor learning errors.  In recent work, we conducted a model-based fMRI experiment, to study the neural substrates of motor adaptation. The prefrontal region was correlated with regressors with the shorter time constants, the medial parietal cortex became more dominant with the intermediate time constants, and the cerebellum was activated with the longer time constants. Finally, we used the fast-slow model to investigate the contextual interference (CI) effect, in which intermixing the learning of different tasks via random schedules reduces performance during training, but enhances long-term retention compared to blocked schedules.  As predicted by our model, only post-stroke participants with good visuo-spatial working memory exhibited the CI effect. Thus, following blocked schedule training, the better the working memory, the worse the long-term retention."

The conference will take place at Arts et Métiers ParisTech, 151 boulevard de l'Hôpital, 75013 Paris , Amphi Fournel, from 13h30 to 15h00.


Published on: 19 March 2013 11:34
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